Tetrahedron Letters, Volume 61, Issue 46 , 12/11/2020

Aspertamarinolides A-C: γ-butenolides from the marine-derived fungus Aspergillus tamarii PSU-MF90

Praphatsorn Saetang, Vatcharin Rukachaisirikul, Souwalak Phongpaichit, Sita Preedanon, Jariya Sakayaroj, Sarinya Hadsadee, Siriporn Jungsuttiwong

Abstract

Three new γ-butenolides, aspertamarinolides A-C, were isolated from the marine-derived fungus Aspergillus tamarii PSU-MF90. Their structures with absolute configurations were elucidated by spectroscopic techniques, electronic circular dichroism (ECD) calculations and specific rotations. A plausible biosynthetic pathway for the isolated γ-butenolides was also proposed.

Document Type

Article

Source Type

Journal

Keywords

Aspergillus tamariiBiosynthetic pathwayECD calculationsMarine-derived fungusγ-Butenolide

ASJC Subject Area

Pharmacology, Toxicology and Pharmaceutics : Drug DiscoveryBiochemistry, Genetics and Molecular Biology : BiochemistryChemistry : Organic Chemistry

Funding Agency

Graduate School, University of Oregon


Bibliography


Saetang, P., Rukachaisirikul, V., Phongpaichit, S., Preedanon, S., Sakayaroj, J., Hadsadee, S., & Jungsuttiwong, S. (2020). Aspertamarinolides A-C: γ-butenolides from the marine-derived fungus Aspergillus tamarii PSU-MF90. Tetrahedron Letters, 61(46) doi:10.1016/j.tetlet.2020.152529

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