Tropical Journal of Pharmaceutical Research, Volume 18, Issue 4, Pages 823-828 , 01/04/2018

Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats

Sarawoot Palipoch, Phanit Koomhin, Chuchard Punsawad, Prasit Suwannalert

Abstract

Purpose: The rate of gastrointestinal adenomatous polyps, often regarded as precancerous lesions, developing into cancer is 40 - 70 %. Endoscopic resection has been the preferred method for treating gastric polyps since the late 1960s. Surgical removal of polyps continues to play an important role in the treatment of polyps; however, the efficacy of such treatment cannot be guaranteed, and polyps may recur. Case presentation: Here, we report a 44-year-old man suffering from gastrointestinal polyps who refused surgical treatment and instead was treated with traditional Chinese herbal medicine (TCHM) for approximately 1 year. The patient was diagnosed with “qi deficiency and dampness syndrome” based on traditional Chinese medicine theory and was treated with the TCHM “strengthen qi and remove dampness formula”, referred to as the shen-ling-bai-zhu powder/decoction. Conclusion: This case suggests that TCHM may play an important role in the treatment of gastrointestinal polyps. Relevant data are, however, limited and a randomized controlled trial is needed to confirm TCHM efficacy in a larger population.

Document Type

Article

Source Type

Journal

Keywords

Case studyGastrointestinal polypsShen-ling-bai-zhu powderTraditional chinese herbal medicine

ASJC Subject Area

Pharmacology, Toxicology and Pharmaceutics : Pharmaceutical ScienceMedicine : Pharmacology (medical)

Funding Agency

Walailak University


Bibliography


Palipoch, S., Koomhin, P., Punsawad, C., & Suwannalert, P. (2018). Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats. Tropical Journal of Pharmaceutical Research, 18(4) 823-828. doi:10.4314/tjpr.v18i4.20

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