Journal of Pediatric Infectious Diseases, Volume 12, Issue 4, Pages 249-255 , 01/12/2017

Malaria in Children: Diagnostic Tools in Resource-Limited Settings

Narong Jaturas, Tooba Mahboob, Nadiah Syafiqah Binti Nor Azman, Tan Tian-Chye, Veeranoot Nissapatorn

Abstract

Malaria contributes to a major reason for the cause of fatality and serious health problems among children mainly in various parts of tropical Africa and Asia. The extraction of DNA plays a vital role in the diagnosis of this life-threatening parasite Plasmodium. Difficulties with existing extraction methods of DNA are increasing with time including detection limits, time duration, sensitivity, availability of chemicals, and cost. Consequently, there is now renewed interest in finding of novel methods for DNA extraction of Plasmodium. However, the extraction of DNA by using microwave irradiation is found to be most convenient and suitable due to its low-cost and usage of common chemical reagents especially for the children in poor resource settings. In addition, the low cost, noninvasive malaria diagnostics tests are needed to carry out particularly for children to avoid accidental infections which may happen due to drawing blood.

Document Type

Review

Source Type

Journal

Keywords

DNA extractionmalarianoninvasiveplasmodium

ASJC Subject Area

Medicine : Pediatrics, Perinatology and Child HealthMedicine : Infectious Diseases



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Citations (Scopus)

Bibliography


Jaturas, N., Mahboob, T., Azman, N., Tian-Chye, T., & Nissapatorn, V. (2017). Malaria in Children: Diagnostic Tools in Resource-Limited Settings. Journal of Pediatric Infectious Diseases, 12(4) 249-255. doi:10.1055/s-0037-1603587

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