Journal of Infection in Developing Countries, Volume 18, Issue 1, Pages 60-65 , 01/01/2024

Seroprevalence and risk factors of Toxoplasma gondii infection among pregnant women

Gholamreza Barzgar, Ehsan Ahmadpour, Mohammad Hasan Kohansal, Sirous Mehrani Moghaddam, Tohid Jafari Koshki, Aleksandra Barac, Veeranoot Nissapatorn, Alok K. Paul, Jelena Micić

Abstract

Introduction: Toxoplasma gondii is an obligate intracellular parasite affecting a broad range of warm-blooded animals, including humans. Infection acquired during pregnancy can be transmitted to the fetus and leading to serious problems such as spontaneous abortion, stillbirth, or severe mental and/or physical handicaps in the child. The purpose of this study was to investigate the seroprevalence of Toxoplasma infection and related risk factors in pregnant woman. Methodology: The study enrolled 1200 serum samples of pregnant women from February-November 2017. Then the samples were tested for the presence of anti-T. gondii antibodies (Ab) using enzyme-linked immunosorbent assay. Results: Out of the 1200 samples, 381 (31.7%) and 41 (3.4%) subjects were positive for IgG and IgM Ab, respectively. Among the evaluated risk factors, the seroprevalence of Toxoplasma infection was not related to the occupation in a significant way. However significant relationship was observed with factors such as; contact with soil, cats, consumption of raw washed vegetables, and washed hands before meals. Conclusions: According to the results, more than two-thirds of pregnant women are susceptible to Toxoplasma infection, hence training health care programs should be provided to prevent infection.

Document Type

Article

Source Type

Journal

Keywords

congenitalELISAseroprevalenceToxoplasma gondii

ASJC Subject Area

Immunology and Microbiology : MicrobiologyImmunology and Microbiology : ParasitologyImmunology and Microbiology : VirologyMedicine : Infectious Diseases


Bibliography


Barzgar, G., Ahmadpour, E., Kohansal, M., Moghaddam, S., Koshki, T., Barac, A., Nissapatorn, V., ... Micić, J. (2024). Seroprevalence and risk factors of Toxoplasma gondii infection among pregnant women. Journal of Infection in Developing Countries, 18(1) 60-65. doi:10.3855/jidc.17832

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